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The Clinical Value of ETCO2 in CPR

Cardiac arrest is a life-threatening condition for patients with cardiovascular disease, Cardiopulmonary resuscitation is the most important treatment for rescuing patients of cardiac arrest. How to monitor the quality of cardiopulmonary resuscitation is very important to improve the survival rate of patients with cardiac arrest. Kingst, an excellent manufacturer who provides quality end tidal co2 monitor for sale, will take you through the application of ETCO2 in CPR.

What is ETCO2?

End-tidal partial pressure of carbon dioxide (PETCO2), it refers to the partial pressure of the carbon dioxide in the exhaled gas at the end of exhalation. Carbon dioxide is normally produced by aerobic metabolism in well-perfused tissues and diffused into the blood, then it is transported through the veins to the body's lungs, where it is finally excreted through breathing.

ETCO2 Measurement

End-tidal carbon dioxide (EtCO2), a measurement used to assess a patient's metabolism, circulation, and ventilation. Studies have shown a linear relationship between EtCO2 levels and coronary perfusion pressure and systemic blood flow during CPR.

EtCO2 measurements are used to confirm the quality of CPR and inform decisions on termination of resuscitation during OHCA.

Rapid increases in EtCO2 during CPR indicate that oxygen transport has improved during cardiac arrest. A persistent or low EtCO2 over time was considered poor quality or ineffective CPR.

In summary, the value of EtCO2 during resuscitation can clearly confirm the quality of CPR, but it is still necessary to improve the clinical application of ETCO2 during resuscitation, reduce the occurrence of complications and improve the treatment rate.


Therefore, the main factors that determine the end-tidal partial pressure of carbon dioxide are the human aerobic metabolic rate, alveolar ventilation, lung perfusion, and cardiac output, and when the patient's lung ventilation and lung perfusion are abnormal, such as in cardiac arrest or pulmonary embolism, then the gap between the patient's end-tidal partial pressure of carbon dioxide and the partial pressure of carbon dioxide in the arterial blood increases. In view of this, theoretically speaking, monitoring end-tidal partial pressure of carbon dioxide can determine whether CPR is effective in patients with cardiac arrest. Here, we recommend you Ekingst waveform capnography machine. The firmness and durability of its products can guarantee the normal use of the machine during CPR.

Capnography measures

It clearly states in AHA, by observing the quantitative analysis of the capnogram, if the PETCO2 is low or drops, then will re-evaluate the quality of CPR and during the ROSC (return of spontaneous circulation after cardiac arrest) phase, firstly, by recording the waveform of EtCO2 or measuring of EtCO2 is required to confirm and monitor endotracheal tube placement. Where feasible, it maybe reasonable to use physiological parameters such as arterial blood pressure or ETCO2 to monitor and optimize CPR quality. This monitoring is dependent on the presence of endotracheal tube (ETT) or arterial catheterization respectively. Adjusting compression goals to achieve an ETCO2 value of at least 10 mmHg, ideally 20 mmHg or higher, may be useful as a marker of CPR quality.